iC3b Human Liquid. In PBS pH 7.2. iC3b is formed by the cleavage of C3b by Factor I in the presence of Factor H CR1 or membrane cofactor protein. Factor I cleavage of C3b to iC3b inactivates and prevents C3b from functioning in the C3 or C5 convertase en
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P/N:
80050-512
- UOM: EA
- UOM Qty: 1
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C3d Human Liquid. In PBS pH 7.2. C3d is formed by the limited digestion of iC3b by trypsin or elastin. The C3d region of C3 contains the portion of the native C3 molecule which is capable of forming a covalent bond attachment to target surfaces under att
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P/N:
80050-518
- UOM: EA
- UOM Qty: 1
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C1 Human Liquid. In 143 mM NaCl 5 mM barbital 500 mM MgCl2 150 mM CaCl2 pH 7.2. C1 is the first component of the classical complement pathway. It is a calcium dependent complex of C1q C1r and C1s subcomponents which are present in the C1 complex at molar
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P/N:
80050-520
- UOM: EA
- UOM Qty: 1
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C1q Human Liquid. In 135 mM NaCl 15 mM sodium phosphate 40% glycerol pH 7.2. Glycoprotein composed of 18 polypeptide chains consisting of three nonidentical subunits A B and C of M.W. 29000 26000 and 19000 respectively. Present in normal human serum at 7
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P/N:
80050-522
- UOM: EA
- UOM Qty: 1
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C1r Human Activated Two-Chain Form Liquid. In 47 mM sodium phosphate 1 mM EDTA pH 7.4. Non-activated form composed of a single-chain glycoprotein. Present in normal human serum at 34 mg/ml.
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P/N:
80050-524
- UOM: EA
- UOM Qty: 1
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C1s Human Activated Two-Chain Form Liquid. In 47 mM sodium phosphate 5 mM EDTA 1 mM benzamidine pH 7.4. Non-activated form composed of a single-chain glycoprotein. Present in human serum at 31 mg/ml.
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P/N:
80050-526
- UOM: EA
- UOM Qty: 1
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C3a Human Liquid. In 135 mM NaCl 15 mM sodium phosphate pH 7.2. Single chain 77 amino acid peptide. Activation of either complement pathway can result in formation of C3-cleaving enzymes (C3 convertases) on target surfaces.
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P/N:
80050-528
- UOM: EA
- UOM Qty: 1
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C2 Human Liquid. In 135 mM NaCl 15 mM sodium phosphate pH 6.0. Single chain glycoprotein present in normal human serum at concentration of 20 mg/ml. Classical pathway activation results in assembly of the C1C4b complex on target surfaces.
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P/N:
80050-530
- UOM: EA
- UOM Qty: 1
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C1-Esterase Inhibitor Human Liquid. In 135 mM NaCl 15 mM sodium phosphate pH 7.4. Single-chain glycoprotein present in normal human serum at 180 mg/ml. Involved in regulation of complement coagulation fibrinolytic and contact (kinin-forming) systems of c
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P/N:
80050-532
- UOM: EA
- UOM Qty: 1
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C3 Human Liquid. In 135 mM NaCl 15 mM sodium phosphate pH 7.2. Glycoprotein composed of two non-identical disulfide-bonded subunits with M.W. of 115000 (a) and 75000 (b). Present in normal human serum at 1.25 mg/ml.
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P/N:
80050-536
- UOM: EA
- UOM Qty: 1
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